Mother 3 is actually going to be playable in English.
Earthbound, this game's prequel (depicted above), is probably one of my favourite games ever, and the only entry in the series to come out in the U.S. It's wonderfully unique and goofy, and I urge you to seek it out.
Oh, and thanks to these guys, you'll be able to play it in English too very soon. Kudos all around.